Research article2012Peer reviewedOpen access
The Chymase Mouse Mast Cell Protease 4 Degrades TNF, Limits Inflammation, and Promotes Survival in a Model of Sepsis
Piliponsky, A.M.; Chen, C-C; Rios, E.J. et al.
Publications
Research article2012Peer reviewedOpen access
Mast Cell Proteoglycans
Rönnberg, Elin; Melo, Fabio Rabelo; Pejler, Gunnar.
Research article2012Peer reviewed
Mast cells express tyrosine hydroxylase and store dopamine in a serglycin-dependent manner
Pejler, Gunnar; Rönnberg, Elin; Calounova, G.
Research article2012Peer reviewed
Serglycin- the master of the mast cell
Pejler, Gunnar; Rönnberg, Elin.
Research article2012Peer reviewed
Tumor-mast cell interactions: Induction of pro-tumorigenic genes and anti-tumorigenic 4-1BB in MCs in response to Lewis Lung Carcinoma
Wensman, Helena; Kamgari, Nona; Johansson, Todd et al.
Research article2012Peer reviewedOpen access
Serglycin Proteoglycan Promotes Apoptotic versus Necrotic Cell Death in Mast Cells
Melo, Fabio Rabelo; Grujic, Mirjana; Spirkovski, Jane et al.
Conference abstract2012
Mast cells protect from post-traumatic spinal cord inflammation in mice by degrading inflammation-associated cytokines via mouse mast cell protease 4
Hendrix, S.; Nelissen, S.; Lemmens, E. et al.
Conference abstract2012
The Mouse Mast Cell Protease 4 is Involved in the Generation of Endothelin-1 in vitro and in vivo
Houde, Martin; Labonte, Julie; Desbiens, Louisane et al.
Conference abstract2012
M-OP-022 Mast cell apoptosis induced by siramesine, a sigma-2 receptor agonist
Spirkovski, Jane; Rabelo Melo, Fabio; Grujic, Mirjana et al.
Conference abstract2012
Retinoic acid inhibits osteoblastic mineralization and promotes osteocyte formation
Lind, T.; Sundqvist, A.; Hu, L. et al.
Research article2011Peer reviewedOpen access
A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation
Chmelar, J; Oliveira, CJF; Rezacova, P et al.
Research article2011Peer reviewedOpen access
Serglycin Is a Major Proteoglycan in Polarized Human Endothelial Cells and Is Implicated in the Secretion of the Chemokine GRO alpha/CXCL1
Meen, AJ; Øynebråten, I; Reine, TM et al.
Review article2011Peer reviewedOpen access
Serglycin: A Structural and Functional Chameleon with Wide Impact on Immune Cells
Kolset, SO; Pejler, Gunnar.
Research article2011Peer reviewed
Lysosomal Membrane Permeabilization Induces Cell Death in Human Mast Cells
Melo, Fabio Rabelo; Lundequist, Anders; Calounova, Gabriela et al.
Research article2011Peer reviewed
Differential regulation of Nr4a subfamily nuclear receptors following mast cell activation
Lundequist, Anders; Calounova, Gabriela; Wensman, Helena et al.
Review article2011Peer reviewed
Biological implications of preformed mast cell mediators
Lundequist, Anders; Pejler, Gunnar.
Research article2011Peer reviewedOpen access
Dual Targets for Mouse Mast Cell Protease-4 in Mediating Tissue Damage in Experimental Bullous Pemphigoid
Lin, Lan; Bankaitis, Eric; Heimbach, Lisa et al.
Research article2011Peer reviewedOpen access
Mast Cell Accumulation in Glioblastoma with a Potential Role for Stem Cell Factor and Chemokine CXCL12
Põlajeva, Jelena; Sjösten, Anna M.; Lager, Nina et al.
Research article2011Peer reviewedOpen access
Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice
Akahoshi, Mitsuteru; Song, Chang Ho; Piliponsky, Adrian M. et al.
Research article2011Peer reviewedOpen access
Heparanase affects secretory granule homeostasis of murine mast cells through degrading heparin
Wang, Bo; Jia, Juan; Zhang, Xiao et al.
Conference abstract2011Open access
Mast cell chymase plays a critical role in bullous pemphigoid in mice
Lin, L.; Bankaitis, E.; Li, N. et al.
Conference abstract2011
The chymase, mouse mast cell protease 4, degrades TNF, limits inflammation, and promotes survival in a mouse model of sepsis
Piliponsky, Adrian; Chen, Ching-Cheng; Rios, Eon et al.
Research article2011Peer reviewedOpen access
A Role for Serglycin Proteoglycan in Mast Cell Apoptosis Induced by a Secretory Granule-mediated Pathway
Melo Fabio Rabelo, Waern Ida, Ronnberg Elin, Abrink Magnus, Lee David M., Schlenner Susan M., Feyerabend Thorsten B., Rodewald Hans-Reimer, Turk Boris, Wernersson Sara, Pejler Gunnar.
Review article2010Peer reviewedOpen access
Mast cell proteases: multifaceted regulators of inflammatory disease
Pejler, Gunnar; Rönnberg, Elin; Waern, Ida et al.
Research article2010Peer reviewedOpen access
Infection of Mast Cells with Live Streptococci Causes a Toll-Like Receptor 2-and Cell-Cell Contact-Dependent Cytokine and Chemokine Response
Rönnberg, Elin; Guss, Bengt; Pejler, Gunnar.
Research article2010Peer reviewedOpen access
Polyamines Are Present in Mast Cell Secretory Granules and Are Important for Granule Homeostasis
García-Faroldi, Gianni; Rodríguez, Carlos E.; Urdiales, José L. et al.
Research article2010Peer reviewedOpen access
Mouse Mast Cell Protease-4 Deteriorates Renal Function by Contributing to Inflammation and Fibrosis in Immune Complex-Mediated Glomerulonephritis
Scandiuzzi, Lisa; Beghdadi, Walid; Daugas, Eric et al.
Conference abstract2010Peer reviewedOpen access
PP-020-09 Protective role of mast cell chymase in house dust mite induced allergic airway inflammation
Waern, Ida; Lundequist, Anders; Pejler, Gunnar et al.
Research article2010Peer reviewedOpen access
The inflammatory response following an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5
Younan George, Suber Freeman, Xing Wei, Shi Tong, Kunori Yuichi, Abrink Magnus, Pejler Gunnar, Schlenner Susan M., Rodewald Hans-Reimer, Moore Francis D. Jr., Stevens Richard L., Adachi Roberto, Austen K. Frank, Gurish Michael F..
Research article2010Peer reviewedOpen access
Accumulation of Ym1 and formation of intracellular crystalline bodies in alveolar macrophages lacking heparanase
Waern Ida, Jia Juan, Pejler Gunnar, Zcharia Eyal, Vlodavsky Israel, Li Jin-ping, Wernersson Sara.
Research article2009Peer reviewedOpen access
Mast Cell Differentiation and Activation Is Closely Linked to Expression of Genes Coding for the Serglycin Proteoglycan Core Protein and a Distinct Set of Chondroitin Sulfate and Heparin Sulfotransferases
Duelli, Anette; Rönnberg, Elin; Waern, Ida et al.
Research article2009Peer reviewed
Reduction with dithiothreitol causes serglycin-specific defects in secretory granule integrity of bone marrow derived mast cells
Braga, Tiago; Ringvall, Maria; Tveit, Heidi et al.
Conference abstract2009Open access
Mast Cell Chymase Regulates Homeostatic Intestinal Barrier Function
Groschwitz, K.R.; Ahrens, R.; Osterfeld, H. et al.
Conference abstract2009Peer reviewed
Mast Cells Regulation of Homeostatic Intestinal Barrier Function is dependent on the Human Chymase Homologue, mcpt4.
Hogan, Simon Patrick; Ahrens, Richard; Osterfeld, Heather et al.
Research article2009Peer reviewed
Serglycin proteoglycan is not implicated in localizing exocrine pancreas enzymes to zymogen granules
Niemann, Carsten U.; Cowland, Jack B.; Ralfkiaer, Elisabeth et al.
Research article2009Peer reviewedOpen access
Critical Role of Mast Cell Chymase in Mouse Abdominal Aortic Aneurysm Formation
Sun, Jiusong; Zhang, Jie; Lindholt, Jes S. et al.
Research article2009Peer reviewedOpen access
Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors
Wensman Helena, Pejler Gunnar, Heldin Nils-Erik, Hellmén Eva.
Research article2009Peer reviewedOpen access
Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism
Groschwitz, Katherine R.; Ahrens, Richard; Osterfeld, Heather et al.
Research article2009Peer reviewedOpen access
Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas
Wensman, Helena; Goransson, Hanna; Leuchowius, Karl-Johan et al.
Research article2009Peer reviewedOpen access
Mouse Mast Cell Protease 4 Is the Major Chymase in Murine Airways and Has a Protective Role in Allergic Airway Inflammation : Protective Role of Chymase in Asthma
Waern, Ida; Jonasson, Sofia; Hjoberg, Josephine et al.
Review article2009Peer reviewed
Novel insights into the biological function of mast cell carboxypeptidase A
Pejler, Gunnar; Knight, Stefan D.; Henningsson, Frida et al.
Research article2009Peer reviewedOpen access
Canine Uterine Bacterial Infection Induces Upregulation of Proteolysis-Related Genes and Downregulation of Homeobox and Zinc Finger Factors
Hagman Ragnvi, Rönnberg Elin, Pejler Gunnar.
Research article2009Peer reviewedOpen access
Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis
Magnusson Sofia E., Pejler Gunnar, Kleinau Sandra, Abrink Magnus.
Review article2009Peer reviewed
Mastcellen – både ond och god : Dags att omvärdera mastcellens roll vid hälsa och sjukdom
Pejler, Gunnar; Nilsson, Gunnar.
Research article2009Peer reviewed
Age-related enlargement of lymphoid tissue and altered leukocyte composition in serglycin-deficient mice
Wernersson, Sara; Braga, Tiago; Sawesi, Osama et al.
Review article2009Peer reviewed
Serglycin proteoglycan: regulating the storage and activities of hematopoietic proteases
Pejler, Gunnar; Abrink, Magnus; Wernersson, Sara.
Conference abstract2009Peer reviewed
A protective role of the murine chymase, mouse mast cell protease 4 (mMCP-4), in a model of allergic inflammation
Waern, Ida; Jonasson, Sofia; Hjoberg, Josephine et al.
Conference abstract2008Open access
Delayed Contraction of the CD8+ T-cell Response Towards Lymphocytic Choriomeningitis Virus Infection in Mice Lacking Serglycin
Grujic, M.; Pravsgaard, Christensen J.; Abrink, M. et al.
Conference abstract2008
Mouse Mast Cell Protease 4 has a detrimental role in anti-GBM-induced glomerulonephritis
Scandiuzzi, Lisa; Åbrink, Magnus; Daugas, Eric et al.
Research article2008Peer reviewed
Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan
Ringvall, Maria; Roennberg, Elin; Wernersson, Sara et al.
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